Wheat germ extract inhibits experimental colon carcinogenesis in F-344 rats
نویسندگان
چکیده
منابع مشابه
Wheat germ extract inhibits experimental colon carcinogenesis in F-344 rats.
It has been demonstrated for the first time that a wheat germ extract prevents colonic cancer in laboratory animals. Four-week-old inbred male F-344 rats were used in the study. Colon carcinogenesis has been induced by azoxymethane (AOM). Ten rats served as untreated controls (group 1). For the treatment of the animals in group 2, AOM was dissolved in physiologic saline and the animals were giv...
متن کاملFermented wheat germ extract (avemar) inhibits adjuvant arthritis.
Anti-inflammatory efficacy of the fermented wheat germ extract (FWGE, Avemar) in the rat adjuvant arthritis (AA) model was examined. To Wistar rats with AA, different doses of FWGE and anti-inflammatory drugs (indomethacin, dexamethasone) as monotherapies were administered and FWGE and either diclofenac or dexamethasone were also given in combination. Besides plethysmographies of the paws, hist...
متن کاملaBatchSystem Using Wheat Germ Extract
modified and unnatural amino acids into protein are possible.t) However, the relatively small amount of product due to early stopping of the translational reaction has been the primary bottleneck for its application. To overcome this problcm, Spirin and co-workers developed a continuous-fiow cell-free translation system, called the CFCF system, in 1988.2) In this system, the protein synthesis i...
متن کاملMethionine restriction inhibits colon carcinogenesis.
Previously, we demonstrated that life-long methionine restriction (MR) in rats increases life span and inhibits aging-related disease processes. The present study examines the effects of MR on the formation of preneoplastic aberrant crypt foci (ACF) in the colon of azoxymethane (AOM)-treated rats. Six-week-old male F344 rats were placed on essential amino acid-defined diets containing either 0....
متن کاملPreventive potential of wheat bran fractions against experimental colon carcinogenesis: implications for human colon cancer prevention.
Epidemiological studies suggest an inverse relationship between the intake of dietary fiber, particularly fiber from cereal grains, and colon cancer risk. Animal model assays have demonstrated that the protective effects of dietary fiber on colon cancer development depend on the nature and source of the fiber. Wheat bran (WB) appears to inhibit colon tumorigenesis more consistently than do oat ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2001
ISSN: 1460-2180
DOI: 10.1093/carcin/22.10.1649